The first volume in the collection, "Particulars of an Indian treaty at Conestogoe between his excellency Sir William Keith, bart, governor of Pennsilvania and the deputies of the Five Nations [July 5-8, 1721]," is a manuscript copy of a printed work by Andrew Bradford, with a preface dated July 26. See Colonial Records, 3: 121. The volume regards a meeting between Sinnekaes, Onondagoes, Cayoogoes, Keith, and James Logan. Freeman Guide: 138 and 1769.

An early settler and prominent citizen in the Moravian heartland near Bethlehem, Pennsylvania, Timothy Horsfield was named justice of the peace when Northampton County was formed out of Bucks in 1752, and was one of those given responsibility for the defence of the local white and Christian Indian populations during the French and Indian War. The Horsfield Papers offer a window onto the tumultuous history of northeastern Pennsylvania during the 1750s and 1760s. Comprised largely of correspondence and related documents between Horsfield, William Parsons, and provincial and military authorities, the collection includes important information on the Native tribes' actions (previously described as "Indian assaults") in the region in 1756 and 1757 and the military and diplomatic response of settlers.